the image shows the the layout image of a Rapid Mixer Granulator machine
BLOGS

5 Common Mistakes to Avoid When Using a Rapid Mixer Granulator

The Rapid Mixer Granulator performs dry mixing & wet granulating by basic design of the special three arm of the mixing impeller and sequences of the mixing process in the cylindrical mixing drum with a rounded connection to the base plate, achieving another special effect. Dry mixing is the first step of the process. Once the products are mixed by the bottom drive rotating tool (impeller), a binder is added to the product. The binder can be sprayed in as part of a binding solution or it can be added in dry form. After this Mixing process, the spraying process occurs through one or more spray nozzles, and by mixing action of the main mixing tool (impeller) and the chopper blade it is quickly dispersed into the product.

Rapid Mixer Granulator Machine is used for the homogeneous mixing of granulation powder used for the production of tablets. It is also used for the process of wet mixing & fast drying. humidifying of the powder in Chemical, Cosmetic, Food, Plastic, Pharmaceutical, General Mixing Industries, etc.

Mistakes to Avoid When Using a Rapid Mixer Granulator:

1. Poor Impeller Blade Design: Proper impeller blade design is essential for efficient mixing. Using blades that are too tiny or incorrectly positioned might cause uneven mixing and granulation. Make sure that the impeller blades are designed to lift and push the material properly, promoting good circulation even at low speeds.

2. Inadequate Chopper Speed: The speed of the chopper blades impacts the size of the granules. Running the chopper at the wrong speeds can result in large or undersized grains. To achieve the best results, set the chopper speed to match the required granule size.

3. Improper Wet Milling Procedure: Wet milling is an important phase in the granulation process. Using a particle size reduction milling machine with improper screen apertures can result in uneven granule sizes. It is critical to utilize a screen built specifically for wet milling and to properly position the milling machine near the discharge port of the high-shear granulator.

4. Ignoring Air-Purged Seals: Air-purged seals are intended to keep an envelope of air around the granulator, preventing powder leakage and contamination. Failure to maintain these seals might result in product loss and reduced quality. Regular inspection and maintenance of air-purged seals are required to ensure their efficiency.

5. Incomplete Clean In Place (CIP) Process: The CIP process is critical for keeping the fast mixer granulator clean and functioning properly. Incomplete CIP methods might result in cross-contamination and product quality concerns. Make sure the CIP skid is properly adjusted and that all exposed surfaces, such as the main chamber, shaft seal, and chopper blade, are well cleaned.

Conclusion:

Avoiding these common mistakes is essential for ensuring the efficient and effective operation of a Rapid Mixer Granulator. Proper impeller blade design, chopper speed adjustment, wet milling process, maintenance of air-purged seals, and thorough CIP processes are key to maximizing the performance and longevity of your equipment. By following these guidelines, you can enhance the quality of your granulation processes and avoid costly errors in your operations.

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Stainless steel tank featuring ladder and steps, designed for ointment liquid oral plant.
BLOGS

How to Revolutionize Pharmaceutical Manufacturing with Ointment and Liquid Oral Plants

In the realm of pharmaceutical and cosmetic manufacturing, precision, efficiency, and adherence to stringent quality standards are paramount. Chemiplant Engineering has been a pioneering force in this arena for over four decades, under the dynamic leadership of Mr. Ved Kalra. From its humble beginnings in Mumbai, the company has grown into a professionally managed, customer-centric entity with a sprawling 50,000 sq. ft. manufacturing unit in Ankleshwar, Gujarat. Specializing in high-quality process equipment, Chemiplant Engineering is renowned for its commitment to timely delivery, optimum quality, and competitive pricing. Let’s explore two of their innovative manufacturing plants, the Cream & Ointment Manufacturing Plant and the Liquid Oral Manufacturing Plant, delving into their applications, features, outputs, and advantages.

Cream & Ointment Manufacturing Plant

Application:

Pharmaceuticals: Creams, Emulsions, Gels, Ointments

Cosmetics: Lotions, Shampoo, Toothpaste

Concept: The plant facilitates the manufacturing of creams, gels, and ointments by blending basic ingredients such as glycol, water, wax, and active ingredients in precise proportions. The process involves heating the glycol and melting the wax in jacketed vessels, followed by the addition of active ingredients in the manufacturing vessel to produce the desired product.

Salient Features:

  • High shear mixers for the water phase and wax phase.
  • Anchor agitator with a high shear homogenizer/emulsifier in the manufacturing vessel.
  • Heating/cooling jackets with temperature control and safety equipment.
  • Hydraulic lifting on the manufacturing vessel top dish for easy product recovery.
  • PLC-based operations with automation, recipe administration, and visualization.
  • Vacuum line for sanitation purposes.
  • Capacity ranges from 20 kgs to 5000 kgs.

Liquid Oral Manufacturing Plant

Application:

  • Syrups
  • Oral Liquids
  • Suspensions

Concept: The Liquid Oral Plant is designed for the production of syrups, oral liquids, and suspensions. It involves a three-tank process comprising sugar melting, manufacturing, and storage vessels. Stirrers and impellers of various types ensure efficient mixing, while heating jackets and homogenizers maintain product quality.

Salient Features:

  • Three-tank process with options for mounting on legs or lugs.
  • High-speed stirrers, paddle-type slow-speed stirrers, and anchor-type stirrers for different viscosities.
  • Heating jackets or limpets for steam heating, all vessels insulated.
  • Electro-polished interconnecting pipelines and TC fittings for easy cleaning.
  • Complete the untouched process with the auto transfer of products and ingredients.
  • Built-in CIP system for vessel cleaning.
  • Load cell-level indicators integrated for precise monitoring.
  • Fully automated PLC-based operations with minimal manual handling.

Conclusion

In conclusion, Chemiplant Engineering’s Cream & Ointment Manufacturing Plant and Liquid Oral Manufacturing Plant exemplify the company’s dedication to innovation, efficiency, and quality. With their advanced features, precise control systems, and adherence to regulatory standards, these plants offer pharmaceutical and cosmetic manufacturers the tools they need to produce high-quality products consistently. By investing in these state-of-the-art manufacturing facilities, companies can optimize their production processes, enhance product quality, and meet the evolving demands of the industry.

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