Stainless steel tank featuring ladder and steps, designed for ointment liquid oral plant.
BLOGS

How to Revolutionize Pharmaceutical Manufacturing with Ointment and Liquid Oral Plants

Written by ChemiplantMarch 27, 2024

In the realm of pharmaceutical and cosmetic manufacturing, precision, efficiency, and adherence to stringent quality standards are paramount. Chemiplant Engineering has been a pioneering force in this arena for over four decades, under the dynamic leadership of Mr. Ved Kalra. From its humble beginnings in Mumbai, the company has grown into a professionally managed, customer-centric entity with a sprawling 50,000 sq. ft. manufacturing unit in Ankleshwar, Gujarat. Specializing in high-quality process equipment, Chemiplant Engineering is renowned for its commitment to timely delivery, optimum quality, and competitive pricing. Let’s explore two of their innovative manufacturing plants, the Cream & Ointment Manufacturing Plant and the Liquid Oral Manufacturing Plant, delving into their applications, features, outputs, and advantages.

Cream & Ointment Manufacturing Plant

Application:

Pharmaceuticals: Creams, Emulsions, Gels, Ointments

Cosmetics: Lotions, Shampoo, Toothpaste

Concept: The plant facilitates the manufacturing of creams, gels, and ointments by blending basic ingredients such as glycol, water, wax, and active ingredients in precise proportions. The process involves heating the glycol and melting the wax in jacketed vessels, followed by the addition of active ingredients in the manufacturing vessel to produce the desired product.

Salient Features:

  • High shear mixers for the water phase and wax phase.
  • Anchor agitator with a high shear homogenizer/emulsifier in the manufacturing vessel.
  • Heating/cooling jackets with temperature control and safety equipment.
  • Hydraulic lifting on the manufacturing vessel top dish for easy product recovery.
  • PLC-based operations with automation, recipe administration, and visualization.
  • Vacuum line for sanitation purposes.
  • Capacity ranges from 20 kgs to 5000 kgs.

Liquid Oral Manufacturing Plant

Application:

  • Syrups
  • Oral Liquids
  • Suspensions

Concept: The Liquid Oral Plant is designed for the production of syrups, oral liquids, and suspensions. It involves a three-tank process comprising sugar melting, manufacturing, and storage vessels. Stirrers and impellers of various types ensure efficient mixing, while heating jackets and homogenizers maintain product quality.

Salient Features:

  • Three-tank process with options for mounting on legs or lugs.
  • High-speed stirrers, paddle-type slow-speed stirrers, and anchor-type stirrers for different viscosities.
  • Heating jackets or limpets for steam heating, all vessels insulated.
  • Electro-polished interconnecting pipelines and TC fittings for easy cleaning.
  • Complete the untouched process with the auto transfer of products and ingredients.
  • Built-in CIP system for vessel cleaning.
  • Load cell-level indicators integrated for precise monitoring.
  • Fully automated PLC-based operations with minimal manual handling.

Conclusion

In conclusion, Chemiplant Engineering’s Cream & Ointment Manufacturing Plant and Liquid Oral Manufacturing Plant exemplify the company’s dedication to innovation, efficiency, and quality. With their advanced features, precise control systems, and adherence to regulatory standards, these plants offer pharmaceutical and cosmetic manufacturers the tools they need to produce high-quality products consistently. By investing in these state-of-the-art manufacturing facilities, companies can optimize their production processes, enhance product quality, and meet the evolving demands of the industry.

Read More
Customized ANFD equipment from Chemiplant Engineering
BLOGS

Exploring the Key Roles of ANFD in the Pharmaceutical Field

Written by ChemiplantMarch 27, 2024

Chemiplants ANFDs are used for solid-liquid separations under pressure & or vacuum. The closed operation ensures consistent product quality, simple validation, and also a required operational safety.
The advanced combination of agitation & hydraulics used in these filters/dryers make them versatile and user-friendly. The resulting wet cakes can be re-slurried and washed thoroughly with water or solvents unlike manual Nutsche Filters and Centrifuges. The discharge of the cake is automatic. If the process demands filtration in a hot or chilled condition the same can be achieved. Finally drying operations can also be conducted within the same equipment.

Chemiplant filters & dryers are successfully installed in the Inorganic and Organic Chemical, Fine Chemical, and most importantly in the Pharmaceutical Industries. These filter dryers can be customized for various processes such as Crystallization, Filtration, Decoloration, Washing & Drying with a variety of options namely different shaft seals, bottom enclosure mechanisms, CIP, etc. The size or selection of a filter/filter-dryer is purely determined by the volume of cake to be handled in a batch & also the nature of the material to be filtered.

Key Roles of ANFD in the Pharmaceutical Field

  • Quick Opening Detachable Bottom: The quick-opening detachable bottom allows for easy access to the interior of the equipment for cleaning, maintenance, and batch changes, ensuring minimal downtime and maximum efficiency.
  • CIP Arrangement: The Clean-in-Place (CIP) arrangement facilitates automated cleaning of the equipment’s interior surfaces, ensuring optimal hygiene and compliance with pharmaceutical standards.
  • Steam Sterilizable: The ANFDs are designed to be steam sterilizable, ensuring that the equipment meets the strict hygiene standards required for pharmaceutical production.
  • Online Sampling Valve: The online sampling valve allows for convenient and representative sampling of the process stream, enabling real-time monitoring of the process and ensuring product quality and consistency.
  • Sintered Metal Filter or Filter Media: The ANFDs can be equipped with a sintered metal filter or other suitable filter media, ensuring efficient and reliable solid-liquid separation for pharmaceutical applications.
  • Agitator with Mechanical Seal: The advanced combination of agitation and hydraulics, including an agitator with a mechanical seal, ensures thorough mixing and efficient filtration, enhancing process efficiency and product quality.
  • Comply with GMP Standards: The ANFDs are designed and manufactured to comply with Good Manufacturing Practice (GMP) standards, ensuring that they meet the highest quality and hygiene standards required in pharmaceutical production.
  • Metal to Metal Sealing Discharge Valve: The metal-to-metal sealing discharge valve ensures reliable and leak-free operation, enhancing operational safety and ensuring product containment during the discharge process.

Conclusion

In conclusion, Chemiplant’s ANFDs are vital in the pharmaceutical industry, offering solid-liquid separation under pressure or vacuum. Their closed operation ensures consistent product quality and operational safety. These filter/dryers can handle various processes like crystallization, filtration, and drying, and are customizable for different needs. Key features include quick-opening detachable bottoms, CIP arrangements, steam sterilizability, and compliance with GMP standards, making them versatile and user-friendly. They play a crucial role in ensuring efficient and reliable pharmaceutical production processes.

Read More